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Ideally, both academic and non-academic institutions should be able to participate in such collaborations to allow for the establishment of very large samples in a straightforward manner. Eites such endeavor requires an easy-to-implement information technology IT framework. Here we present the requirements for a centralized framework and describe how they can be met through a modular IT toolbox. Psychiatric genetic research has reached a crucial point in time.
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Moreover, whole genome or whole exome sequencing are gaining popularity, with both case-control and family-based designs being applied. This not only increases the level of sample heterogeneity but also introduces massive challenges to information technology IT. Particularly in the United States, these repositories and databases are widely used and provide platforms for biomaterial and data sharing. For siges funded projects, depositing of biomaterial and data may even be mandated by law.
Nonetheless, there is a need adbert highly flexible IT frameworks that allow for ever-growing networks of research groups that differ wites size, expertise, research foci, or funding but are joined by the wish to collaborate in the establishment of large samples. The IT challenges that such frameworks have to face are the massive data amount, different data quality, heterogeneous IT sources and, most importantly, non-standardized metadata.
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